Submissions

Login or Register to make a submission.

Author Guidelines

Submission

The document needs to be prepared in English language. The manuscript needs to be documented, maintaining double-spacing between lines along with a large margin. All the pages of the document needs to be numbered in a sequence, including those containing figures, tabular columns, acknowledgements, references, etc. The documents containing the manuscript should be a Word file or PDF file. When submitting a complete study through the manuscript submission system, please ensure that all components are uploaded as distinct files:

  • The manuscript
  • A compressed file of all Figures related to the manuscript
  • A compressed file of all Tables related to the manuscript
  • A compressed file including any supplementary materials
  • A compressed file containing the raw data

Terms of Submission

Submission of a manuscript to the Nature Reviews Immune Inflammation journal directly implies that all the authors have read and agreed to the journal’s guidelines. The content present in the manuscript after publication will be freely available to all the potential readers over the Internet for noncommercial use. The content provided by the authors in the manuscript should at no point of time breach the Copyrights or rights of a third party. The manuscript submitted should not be published or submitted for consideration in any other journal.

Peer-Review Process

The journal follows rigorous single-blind peer-review process. This is done with the aim to minimize the possibility of a biased opinion when the reviewers know who the authors are and from where they come from, ensuring a responsible and ethical environment.

Article Types

Nature Reviews Immune Inflammation welcomes submissions in the following article types: Research Article, Short Communication, Review Article, Perspective, Method and Protocol, Editorial, Announcement, Commentary and Correspondence.

Article Type Description Word Limit Abstract / Structure Other Requirements
Research Article Reports of new research findings or conceptual analyses that make a significant contribution to knowledge 3000-6000 words and 4–6 figures. Supplement file is no limit. Yes, Structured Data and Code Availability
IRB Statement
Short Communication Brief observations and research reports in a concise format. 1500-3000 words and 1–3 figures. Yes, Structured  
Review Article Overview of developments in fields or the current lines of thought. Synthesizes multiple sources of information and has long list of references. Emphasis is more factual and less on opinion. 3000-12000 words, 2–6 figures and tables. Yes, unstructured  
Perspective Personal opinion on a topic, often with a novel/imaginative approach to a provocative question with an engaging though rigorous investigation that enhances the understanding of the subject, including new developments, and moderate referencing 3000-5000 words Yes, unstructured  
Method Procedural method in the design and implementation of an experiment or study 3000-12000 words, figures no limit Yes, unstructured Troubleshooting
Protocol Procedural protocol in the design and implementation of an experiment or study 3000-12000 words, figures no limit Yes, unstructured Troubleshooting
Opinion Personal opinions on a topic enhances the understanding of the subject   No  
Editorial To convey an opinion, or overview of an issue, by the Editor or someone invited by the editor   No  
Announcement Sharing factual information or acknowledgements from the journal or its owners that is not dissemination of knowledge, research, or opinion.   No  
Commentary Expert opinion from one or more people (who may agree or disagree) on a published work, current understanding/status of an area, or how practice should be undertaken. Generally with references.   No  
Correspondence A letter, or response to a letter, sent to the journal to raise a point of interest, discuss a difference of opinion or encourage participation   No  
Abstracts Abstracts published as articles, either individually, under sections, or as an entire collection from a conference, and materials related to them, such as Introductions, Author Indices etc. Up to 5000 words No Conflict of Interest
Analysis Overview of developments in fields or the current lines of thought. Synthesizes multiple sources of information and has long list of references. Emphasis is more factual and less on opinion. 3000-12000 words. Yes, unstructured Data and Code Availability

All the Research Article manuscripts that are submitted to Open Access journal need to be submitted in the following format:

  • Cover letter
  • Title Page
  • Abstract
  • Introduction
  • Materials and Methods
  • Results and Discussion
  • Conclusion
  • Acknowledgements
  • References

Cover letter

  • Along with the manuscript, a mandatory cover letter needs to be submitted.
  • Declaration of any potential conflict of interest.
  • A consent confirming the approval by all the co-authors to submit the manuscript.
  • Confirmation that the content of the manuscript has not been published or submitted for publication elsewhere.
  • Consent confirming that the manuscript has not been published or is under consideration for publication with any other journal.
  • If the manuscript is being submitted as part of a special issue, then the special issue title needs to be mentioned in the cover letter along with the manuscript title.

Abstract

An abstract must have a short and precise title that describes the nature of the investigation. An abstract of 200–250 words needs to be prepared, giving a brief outline of the work that has been carried out.

Title and Authorship Information

The following information should be included:

  • Title of the paper
  • Author complete names
  • Complete mailing address of the institution
  • Email addresses

Introduction

In an era marked by rapid advancements and evolving paradigms in [specific field], the importance of thorough and innovative research cannot be overstated. This study addresses [specific topic or issue], aiming to bridge a significant gap in our understanding of [key aspect of the field]. By investigating [specific phenomena, mechanisms, or theories], we aspire not only to expand theoretical knowledge but also to provide practical insights that can inform policy decisions, guide future research initiatives, and influence real-world applications.

The significance of this work lies in its potential to challenge existing frameworks and introduce fresh perspectives on [central issue]. Our research is grounded in a robust methodological framework that combines [primary methods or technologies] with [complementary methods or analytical tools], ensuring rigorous and reliable outcomes. Through this comprehensive approach, we aim to uncover dimensions of [subject or field] that have previously remained unexplored.

Key highlights of the present study include:

  • Identification of [new findings or trends]: Revealing novel patterns or trends that have not been adequately addressed in previous literature.
  • Development of [new models, theories, or frameworks]: Proposing innovative models, theories, or frameworks that offer new angles on [research subject].
  • Application of [advanced methods or technologies]: Demonstrating the effectiveness of cutting-edge methodologies or technologies that enhance the depth and breadth of our analysis.
  • Implications for [practice, policy, or theoretical development]: Discussing how the findings can be translated into actionable recommendations for practitioners, policymakers, or theorists.

Overall, this research contributes to a deeper understanding of [core research question], while simultaneously opening up avenues for further inquiry. It underscores the value of interdisciplinary approaches and collaborative efforts in tackling complex challenges within [relevant field].

By presenting these contributions, this study seeks to engage with a broad audience of researchers, practitioners, and policymakers, fostering dialogue and advancing the collective knowledge in [field of study].

Materials and Methods

By submitting your manuscript to the journal, you grant permission for the materials detailed in the manuscript—including all associated data—to be freely accessible to researchers and scientists for non-commercial purposes. This sharing will be conducted while strictly maintaining the confidentiality of participants.

Results

In this section, authors should present the principal findings of their experiments. This includes all significant observations, statistical analyses, and an initial interpretation of the importance and implications of the study results.

Discussion

The Discussion section provides authors with the opportunity to delve into the meaning and implications of their findings. Here, they should evaluate the significance of the results, how they fit into the existing body of knowledge, and discuss the outcomes of any statistical analyses. Additionally, this section can cover the limitations of the study, potential directions for future research, and possible practical applications.

Conclusion

The conclusion provides an opportunity to synthesize the key findings of the study, reflecting on their broader implications. Here, we evaluate the significance of our results, demonstrating how they contribute to and extend the existing body of knowledge. Our statistical analyses have revealed [specific outcomes or trends], underscoring the importance of these findings within the field. We also acknowledge the limitations of our study, which provide valuable insights for refining future research methodologies. Finally, this work highlights potential practical applications and suggests promising avenues for further investigation, encouraging continued exploration into [related areas or unresolved questions].

Acknowledgments

In this section, the author is free to mention the individuals or contributors who have directly or indirectly provided any technical assistance to the original work and would not be considered to meet the criteria for authorship. The authors must seek the consent of the individual or contributors, whom they would like to mention in this section as a matter of courtesy.

References

Vancouver System of referencing. A unique Arabic number is assigned to every citation mentioned in the manuscript. The numbers are assigned in a sequential order. The same reference numbered has to be mentioned when the citation is repeated. The numbering can be shown in brackets or as superscript without brackets.

Reference numbering: All the references that are being used are numbered in the order they are first mentioned. The reference numbers for tables and legends have to be used along with the parenthesis. In the event of reuse of the earlier reference, the same reference number needs to be used.

Format for References: The authors' surname must be followed by their initials, the abbreviation et al is used after the first six authors names; followed by the title of the paper; then the title of the journal (abbreviated according to the style in the indexing platform [www.roa.nih.org]), if the journal is not indexed, the full title of the journal needs to be mentioned; year in which it was published; volume number; first and last page numbers. Punctuations need to be carefully and correctly used.

Examples of References:

For journal articles:

Article with less than 6 authors:

Chen Z, Makgasa M. Colo-Ostium Fistula Caused by Colonic Foreign Body. Nature Reviews Immune Inflammation. 2025;1(1):3216-20.

Article with more than 6 authors:

Brian H, Christina CB, Michael C2, Mark CS1, Casey M3, Mani D3, et al. ECMO Cannulation Criteria in COVID-19 (ECC-VID) and Obesity: A Literature Review and Retrospective Cohort Analysis. Nature Reviews Immune Inflammation. 2025;1(1):3197-205.

For books:

Tiff AK, editor. Induced gene mutation as a result of hypertension: clinical study. Denver: Appleton-centinary-Crofts; 1818.

For References from chapters in books:

Richard MV, Stephenie A. Outbreak of H1N1 virus. In: Geoffrey M, editor. Spread of epidemics. 2nd ed. California: SJ Brooks; 2001. p. 134-137.

For electronic media:

Parker WJ. Gene expression under thermal stress. Genomical Online Journal. 2011 [cited 2011 Sep 27]. Available from: http://genomicgenes.cgen.org.

Tables

The tables that are being used in the manuscript need to be numbered accordingly. Table title needs to be stated for all the tables that are being used. A heading need to be mentioned for each column. Mention the reference source if the data is taken from another source. The content and explanation about the table need to be mentioned in the note below and not in the heading.

Personal communication

Refrain from the usage of any personal information. Avoid mentioning Email addresses and contact information, class notes, information from interviews, class handouts, since these cannot be retrieved by others. However, the name of the person and the date of communication can be mentioned in parentheses.

Web and Media

Information obtained over the Internet in due course of time may be deleted or changed, so it is always advisable to keep a hard copy of the information and a track of the source from where it has been extracted.

Preparation of Figures

  • JPEG (recommended for photographic images, less suitable for graphical images)
  • TIFF (recommended for images)
  • The resolution of the Image should be approximately 300 dpi (dots per inch)

Proofs

An Email along with the link directing to the proof in PDF format, which can be freely downloaded, would be sent to the corresponding author. Once the PDF is downloaded, the corrections need to be sent back to the concerned managing editor within 3 days. An Email notification needs to be sent if the article correction process would be delayed. Authors facing a challenge to make any corrections to the electronic copy may consider taking a printout and making the changes on the hard copy.

Copyrights

Submission of a manuscript to the Nature Reviews Immune Inflammation journal directly implies that all the authors have read and agreed to the journal's guidelines. The content present in the manuscript after publication will be freely available to all the potential readers over the Internet for non-commercial use.

The content provided by the authors in the manuscript should at no point of time breach the Copyrights or rights of a third party. The manuscript submitted should not be published or submitted for consideration in any other journal. Manuscripts with plagiarized content will not be considered for the peer-review process.

Disclosure Policy

Disclosure statements of all the co-authors need to be sent at the time of submission. Manuscripts submitted without the disclosure statement will be considered incomplete and may not be considered to be reviewed.

At the external peer-review stage, the authors are required to send signed copies of the following statements:

  • Authors contribution.
  • A statement of Conflict of interest.
  • Written Acknowledgments-consent of cited content and individuals.
  • Personal communications-written consent of cited content and individuals.
  • In the event of usage of any copyrighted/protected material —A signed authorization from author and publisher.
  • A signed copy of the subject whose clinical images are presented for study.

Reprints

Reprints would be available 2 weeks after the publication of the article in the concerned journal. For information and price, contact by sending an Email to the editor at editorial@naturerii.com

Submission Preparation Checklist

All submissions must meet the following requirements.

  • This submission meets the requirements outlined in the Author Guidelines.
  • This submission has not been previously published, nor is it before another journal for consideration.
  • All references have been checked for accuracy and completeness.
  • All tables and figures have been numbered and labeled.
  • Permission has been obtained to publish all photos, datasets and other material provided with this submission.

Specifications for Uploading Journal Submission Materials

  • Title page (should be uploaded in Word format)
  • Manuscript (should be uploaded in Word format. For the revised document, both the clean version and the version with revision marks should be provided)
  • Acknowledgements (should be uploaded in Word format)
  • Figure Legends (should be uploaded in Word format)
  • Figures (should be uploaded in a compressed package. Jpg or png format is recommended for the pictures)
  • Tables (should be uploaded in Word format)
  • Supplementary Materials (can be uploaded in any form of a compressed package, Excel, or Word)
  • Raw Data (can be uploaded in any form of a compressed package, Excel, or Word)

Abstract format

  • Research Article, Short Communication: A structured abstract is needed, usually covering objective, methods, results, and conclusion, to clearly outline the study's core content and findings.
  • Review Article, Perspective, Method, Protocol, Analysis: An unstructured abstract is required, offering an overall summary of the article without dividing it into specific sections, with more focus on the general summary and viewpoint presentation.
  • Other types of articles: No abstract is needed. You can submit "No abstract available" in the system.

References format in citation

  • For references with less than six authors, all authors should be listed, and a doi link should be attached at the end. For example: Shiogama H, Watanabe M, Kim H, & Hirota N. (2022). Emergent constraints on future precipitation changes. Nature, 602(7898),612-616. https://doi.org/10.1038/s41586-021-04310-8
  • For references with more than six authors, only the first six authors should be listed, and the remaining authors should be replaced with "et al", and a doi link should be attached at the end. For example: Huang HJ, Liu C, Sun XW, Wei RQ, Liu LW, Chen HY, et al. (2024) The rheumatoid arthritis gut microbial biobank reveals core microbial species that associate and effect on host inflammation and autoimmune responses. iMeta, 3(5). https://doi.org/10.1002/imt2.242

References format in system

     [1] Shiogama H, Watanabe M, Kim H, & Hirota N. (2022). Emergent constraints on future precipitation changes. Nature, 602(7898),612-616. https://doi.org/10.1038/s41586-021-04310-8

     [2] Huang HJ, Liu C, Sun XW, Wei RQ, Liu LW, Chen HY, et al. (2024) The rheumatoid arthritis gut microbial biobank reveals core microbial species that associate and effect on host inflammation and autoimmune responses. iMeta, 3(5). https://doi.org/10.1002/imt2.242

References format in manuscript

  • In the article, references should be placed in square brackets before the full stop of a sentence. For example: Recent advancements in integrating machine learning with multi-omics have been pivotal in identifying key molecular signatures in sarcoma [1].
  • In the article, references should be placed in square brackets before the full stop of a sentence. Two articles are cited continuously. Whether the serial number of the literature is continuous or not, it should be separated by commas. For example: Recent advancements in integrating machine learning with multi-omics have been pivotal in identifying key molecular signatures in sarcoma [1,2].
  • In the article, references should be placed in square brackets before the full stop of a sentence. When a number of consecutive references are cited, the serial number of the first article and the serial number of the last article should be separated by a horizontal bar. For example: Recent advancements in integrating machine learning with multi-omics have been pivotal in identifying key molecular signatures in sarcoma [1-5]

Word Limit

  • Research Article: 3000-6000 words and 4–6 figures. Supplement file is no limit.
  • Review Article: 3000-12000 words, 2–6 figures and tables.
  • Short Communication: 1500-3000 words and 1–3 figures.
  • Perspective: 3000-5000 words
  • Method: 3000-12000 words, figures no limit
  • Protocol: 3000-12000 words, figures no limit
  • Abstracts: Up to 5000 words 8. Analysis: 3000-12000 words.
  • Other types of articles: words and figures no limit.

All the Research Article and Short Communication manuscripts that are submitted to Open Access journal need to be submitted in the following format:

  • Cover letter
  • Title Page
  • Abstract
  • Introduction
  • Materials and Methods
  • Results
  • Discussion
  • Conclusion
  • Abbreviations
  • Acknowledgements
  • References

The Acknowledgements section should include the following parts:

  • Author contributions: This part details each author’s specific roles in the research, like who handled the study design, data collection, analysis, and writing. It clarifies author responsibilities and credit, enhancing research transparency. It’s typically at the paper’s end or in a separate author contribution statement.
  • Ethics approval and consent to participate: For studies involving human subjects or animal experiments, this part confirms whether ethical committee approval and participant consent were obtained. It’s crucial for ensuring ethical compliance and is usually in the methods section or a separate ethics statement.
  • Funding information: This lists the research’s funding sources, including funding agencies and project numbers. It helps understand financial support and acknowledges funders. It’s typically at the paper’s end or in a separate funding statement.
  • Competing Interests: Authors declare any potential conflicts of interest that might affect the research’s fairness, such as financial ties to companies. If none exist, a statement like “The authors declare no competing interests” is used. It’s usually at the paper’s end or in a separate conflict of interest statement.
  • Data Availability: This part explains if the research data is accessible and how to obtain it. Some journals require data sharing for reproducibility and transparency. It’s typically at the paper’s end or in a separate data availability statement.
  • Thanks: The thanks section acknowledges individuals or institutions that assisted but didn’t directly participate in the research.

Copyright Notice

Submission of a manuscript to the Nature Reviews Immune Inflammation journal directly implies that all the authors have read and agreed to the journal's guidelines. The content present in the manuscript after publication will be freely available to all the potential readers over the Internet for non-commercial use.

The content provided by the authors in the manuscript should at no point of time breach the Copyrights or rights of a third party. The manuscript submitted should not be published or submitted for consideration in any other journal. Manuscripts with plagiarized content will not be considered for the peer-review process.

Privacy Statement

Effective Date: October 1, 2024

At Life Conflux Press, we are committed to protecting your privacy and ensuring the security of your personal information. This Privacy Policy outlines how we collect, use, store, and protect your data when you interact with our website, services, and products. By using our services, you agree to the terms outlined in this policy.

  1. Information We Collect

We may collect the following types of information:

  • Personal Information: Name, email address, phone number, mailing address, and other contact details.
  • Payment Information: Credit card details, billing address, and transaction history (processed securely through third-party payment processors).
  • Technical Data: IP address, browser type, device information, operating system, and usage data collected through cookies and similar technologies.
  • User Content: Manuscripts, comments, reviews, or other content you submit to us.
  1. How We Use Your Information

We use the information we collect for the following purposes:

  • To provide and improve our services, including publishing, customer support, and website functionality.
  • To process transactions and send you order confirmations, invoices, and updates.
  • To communicate with you about our products, services, promotions, and events (you may opt out at any time).
  • To analyze website usage and trends to enhance user experience.
  • To comply with legal obligations and protect our rights and interests.
  1. Information Sharing and Disclosure

We do not sell your personal information to third parties. However, we may share your information in the following circumstances:

  • Service Providers: We may share data with trusted third-party vendors who assist us in operating our website, processing payments, or delivering services.
  • Legal Requirements: We may disclose information if required by law or to protect our rights, property, or safety, or that of others.
  • Business Transfers: In the event of a merger, acquisition, or sale of assets, your information may be transferred to the new owner.
  1. Cookies and Tracking Technologies

We use cookies and similar technologies to enhance your experience on our website. Cookies are small text files stored on your device that help us recognize you and remember your preferences. You can manage or disable cookies through your browser settings, but this may affect your ability to use certain features of our website.

  1. Data Security

We implement industry-standard security measures to protect your personal information from unauthorized access, alteration, disclosure, or destruction. These measures include encryption, secure servers, and regular security audits. However, no method of transmission over the internet or electronic storage is 100% secure, and we cannot guarantee absolute security.

  1. Your Rights

You have the following rights regarding your personal information:

  • Access: Request a copy of the personal data we hold about you.
  • Correction: Request that we correct or update inaccurate or incomplete information.
  • Deletion: Request that we delete your personal data, subject to legal obligations.
  • Opt-Out: Unsubscribe from marketing communications at any time by clicking the "unsubscribe" link in our emails.

To exercise these rights, please contact us using the information provided below.

  1. International Data Transfers

If you are located outside the region where our servers are based, your information may be transferred to and processed in countries with different data protection laws. We will take steps to ensure that your data is treated securely and in accordance with this Privacy Policy.

  1. Children's Privacy

Our services are not intended for individuals under the age of 16. We do not knowingly collect personal information from children. If we become aware that we have inadvertently collected such information, we will take steps to delete it promptly.

  1. Changes to This Privacy Policy

We may update this Privacy Policy from time to time to reflect changes in our practices or legal requirements. We will notify you of any significant changes by posting the updated policy on our website and updating the effective date. We encourage you to review this policy periodically.

  1. Contact Us

If you have any questions or concerns about this Privacy Policy or our data practices, please contact us at:

  • Email: privacy@lifeconfluxpress.com
  • Phone: +86 15855142612
  • Mailing Address: Life Conflux Press Limited