Advancements in Understanding Neurogenesis in Alzheimer's Disease: Current Research and Insights

Chenlu Zhu

doi:10.71321/4gjht115

Authors

Chenlu Zhu The First Affiliated Hospital of Shandong First Medical University

DOI:

https://doi.org/10.71321/4gjht115

Keywords:

Alzheimer's disease, Dentate gyrus, Neurogenesis, Rbm8a gene

Abstract

Alzheimer's disease (AD) is increasingly impacting the aging global population, with its prevalence and mortality rates rising steadily. This trend severely affects the quality of life and intensifies the economic strain on both families and society. Despite ongoing research, effective treatments remain elusive. However, enhancing neurogenesis in the hippocampal dentate gyrus (DG) to promote the formation of new neurons and replace those lost in AD patients' hippocampus holds promise as a potential strategy to improve cognitive and memory functions, offering hope for delaying or even treating the disease.

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