Research Progress in Multimodal Guidance for Brain Tumor Surgeryand Preservation of Functional Brain Networks

Fengchun Mu; Huaixu Li; Ming Yang; Jinghai Wan

doi:10.71321/1wsxr932

Authors

Fengchun Mu Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Huaixu Li Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Ming Yang Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Jinghai Wan Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

DOI:

https://doi.org/10.71321/1wsxr932

Keywords:

Brain tumor, Multimodal techniques, Functional brain networks, Neuroprotection

Abstract

The evolution of brain tumor surgery has progressed from "microsurgery" to "precision neurosurgery," currently entering a new stage characterized by the deep integration of multimodal technologies and the concept of preserving functional brain networks. This article systematically reviews the current state of research on preserving brain functional networks during brain tumor surgery. It summarizes the composition of brain functional networks, the impact of brain tumors on these networks, the classification of multimodal technologies, and the application progress of protecting key functional networks during brain tumor surgery. It emphasizes that precision surgical strategies based on preserving brain functional networks can significantly improve patient quality of life and provide a new paradigm for translational brain science research. Despite progress, key challenges remain, including interindividual functional variability, intraoperative brain shift, and the limited reproducibility of non-traditional network mapping. Future research should focus on dynamic monitoring of functional networks, long-term functional prognosis correlation analysis, and cross-modal data fusion integrated with artificial intelligence to establish new precision surgery standards guided by multimodal functional network preservation.

Author Biography

Jinghai Wan, Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

Director of the Department of Neurosurgery, National Cancer Center; Chief Physician; Doctoral Supervisor

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